Functionalized porous silica&maghemite core-shell nanoparticles for applications in medicine: design, synthesis, and immunotoxicity

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Functionalized porous silica&maghemite core-shell nanoparticles for applications in medicine: design, synthesis, and immunotoxicity

AIM To determine cytotoxicity and effect of silica-coated magnetic nanoparticles (MNPs) on immune response, in particular lymphocyte proliferative activity, phagocytic activity, and leukocyte respiratory burst and in vitro production of interleukin-6 (IL-6) and 8 (IL-8), interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), and granulocyte macrophage colony stimulating factor (GM-CSF)....

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Fe3O4/SiO2/(CH2)3N+Me3Br3– core–shell nanoparticles: An efficient catalyst for the synthesis of functionalized 5-oxo-hexahydroquinolines

The four-component Hantzsch condensation reaction of dimedone, ethyl acetoacetate, ammonium acetate, and various aromatic and aliphatic aldehydes in the presence of catalytic amount of a magnetic nanoparticle-supported tribromide, as a green catalyst, under solvent‐free conditions at 80 °C affords functionalized 5-oxo-hexahydroquinolines in good to excellent yields. The magnetic Fe3O...

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ژورنال

عنوان ژورنال: Croatian Medical Journal

سال: 2016

ISSN: 0353-9504,1332-8166

DOI: 10.3325/cmj.2016.57.165